World Health Organization (WHO) Director-General Tedros Adhanom Ghebreyesus this week said the variant has spread at a rate not seen with other variants. WHO reported that 77 countries had detected the variant so far, with some countries seeing the number of new cases doubling over the last two weeks.
New Mexico became the first state to require booster shots for some state employees, such as health care workers and educators, with officials citing "incontrovertible" evidence that immunity wanes over time.
Other governments have considered a booster mandate, but businesses and universities have pushed ahead with their own mandates in the meantime.
The NFL had resumed some strict protocols, such as mask mandates and required spacing, but the league took the bold step of requiring eligible coaches and staff to receive a booster by Dec. 27 in a bid to keep the season on track and on schedule.
And the Metropolitan Opera on Wednesday announced that all eligible adult employees and audience members must have a booster shot in order to enter, The New York Times reported.
The Washington Post also informed employees they would need a booster by Feb. 15, 2022, and weekly testing starting Jan. 31. The mandate will apply to all major office locations, with on-site testing clinics in its Chicago, San Francisco, New York and Washington offices.
"Booster shots are now incorporated into our mandatory vaccination policy — that is, they are a condition of employment, regardless of your location," an email sent to employees on Dec. 10 said.
Education has seen the most widespread embrace for boosters: Several universities have taken the running and introduced a booster requirement for students and staff.
Several Massachusetts institutions announced mandates, including the University of Massachusetts-Amherst, Boston College, Northeastern University, Emerson College and Smith College.
Syracuse University, claiming to be among the first U.S. universities to require a COVID-19 vaccination to attend, announced that it would also require boosters for any student or faculty who regularly access the campus.
NYU, which this week pushed all final exams online, announced Tuesday that all eligible members of the faculty and student body must receive a booster by Jan. 18, 2022 and upload proof of the vaccination.
Georgetown gave students and faculty until Jan. 21 to do the same, and George Washington University set a deadline of Feb. 1.
Three Michigan schools – Michigan State University, the University of Michigan and Wayne State University – as well as two private universities in Minnesota, the University of Notre Dame, Wesleyan University and the University of New Mexico have followed suit and announced booster mandates, indicating the trend will only gain momentum at other institutions.